Acrysol®Castor Oil Derivatives
Acrysol range is non ionic solubiliser and emulsifier obtained by reacting hydrogenated castor oil with ethylene oxide. They have ability to solubalise and emulsify oils soluble ingredients like vitamins, perfumes, essential oils and other hydrophobic pharmaceuticals and covert them into clear transparent solution or stable emulsion respectively. It improves the solubility of poorly soluble drugs (BCS class II and class IV).
Acrysol range improves water solubility of major water insoluble products. It is compatible with most of the commonly used ingredients. It helps to solubilize different pharmaceutical active ingredients like Acetaminophen, Bromhexine HCL, Dextromethorphan HBr, Povidone iodine, Loxapine Succinate, Vitamins like vitamin A palmitate, vitamin D, vitamin E acetate etc.
It is also used as solubilizer and stabilizer for oils and perfumes in cosmetic industries.
It is generally used 3.0% to 5.0% w/w of API to improve dissolution of poorly soluble active ingredients like Cefuroxime Axetil, Cefpodoxime proxetil, Albendazole etc.
It should be mixed with API with or without heating and then dissolved in vehicle ( Aqueous / Non aqueous ).
Acrysol range is excellent versatile emulsifying agent. It emulsifies major hydrophobic substances like fatty acids, fatty alcohols, mineral oil etc.
Acrysol range improves moisturizing effect and soft feeling.
Acrysol range solubilizes insoluble oily substances in aqueous system and hence it improves transparency and shining.
In cosmetic formulations, it impacts elegance, appearance of products such as shaving gel, hair styling gel, hand wash gel etc. In pharmaceutical syrup formulations, it improves transparency.
Acrysol range retards volatilities of solvents. It can be used for highly volatile products like after shav lotion, perfumes etc. to retain its effect for longer period.
Acrysol range improves film forming capacity and flow properties. Acrysol is preferred in cream, lotion, lipstick etc. to improve film forming capacity.
Acrysol masks unpleasant taste and odor of typical formulations like pharmaceutical syrup containing alcohols and suspension like artemether and lumefantrine suspension.
Acrysol improves solubility of the propellant in aerosol in aqueous phase.
Acute and chronic toxicity test in animals have shown that Acrysol grades are essentially non-toxic and non-irritant material.
Two years from date of manufacturing in intact condition.
20 kg net in plastic carboy.