Acrypol®
Carbomer / Acrylates CopolymersAcrypol range is a synthetic high molecular weight cross linked water soluble polymer of Acrylic acid, which is known as "Carbomer"/ "Acrylates polymers". It is widely used in cosmetic, pharmaceutical and household industries.
It is available in powder and liquid form, which is soluble in water, alcohols and glycols. Before neutralization, pH of Acrypol grade solution lies between 2.5 and 3.0.
General Application
- Thickening - To produce wide range of viscosity and flow property
- Suspending - Suspending of insoluble ingredients like cosmetic beads
- Stabilizing - To provide emulsification and stabilization of high content of oils and waxes.
- Sustain and control release - Allows controlled drug release in solid dosage form in less concentration.
Personal Care / Home Care
The traditional grades are chemically Carbomers. These are cross linked polyacrylic acid polymer, available in white powder. They are rheology modifiers, capable to provide vast viscosity profile. They work at neutral pH and form sparkling clear gel, hydro-alcoholic gels and creams.
| Grade | Availability | INCI | Key Benefits |
|---|---|---|---|
| Acrypol 940 | Powder | Carbomer |
|
| Acrypol 980* | |||
| Acrypol 990* | Powder | Carbomer |
|
| Acrypol 996 | Powder | Carbomer |
|
| Acrypol 934 | Powder | Carbomer |
|
| Acrypol 974* | |||
| Acrypol 941 | Powder | Carbomer |
|
| Acrypol 971* | |||
| Acrypol 956* | Powder | Carbomer |
|
| Acrypol 950 | Powder | Carbomer |
|
| Acrypol 1342 | Powder | Acrylates/C10-30 Alkyl Acrylate Crosspolymer |
|
| Acrypol 1382* | Powder | Acrylates/C10-30 Alkyl Acrylate Crosspolymer |
|
These Acrypol grades are easy-to-disperse polymers, designed to get faster wetting/ self wetting property to shorten dispersion time.
| Grade | Availability | INCI | Key Benefits |
|---|---|---|---|
| Acrypol ET2020* | Powder | Acrylates/C10-30 Alkyl Acrylate Crosspolymer |
|
| Acrypol ELT-10* | Powder | Carbomer |
|
| Acrypol ELT-20* | Powder | Acrylates/C10-30 Alkyl Acrylate Crosspolymer |
|
| Acrypol ELT-21* | Powder | Acrylates/C10-30 Alkyl Acrylate Crosspolymer |
|
These Acrypol grades are suitable for O/W or W/O emulsion.
| Grade | Availability | INCI | Key Benefits |
|---|---|---|---|
| Acrypol TR-1* | Powder | Acrylates/C10-30 Alkyl Acrylate Crosspolymer |
|
| Acrypol TR-2* | Powder | Acrylates/C10-30 Alkyl Acrylate Crosspolymer |
|
| Acrypol TR-3* | Powder | Acrylates/C10-30 Alkyl Acrylate Crosspolymer |
|
These liquid Acrylates rehology modifiers designed to suspend, stabilise, thicken and enhance the appearance of surfactant based cosmetic and house hold formulations. They provide synergetic effect with salt in surfactant system. They have high ion tolerance and provide stable viscosity in high alkaline system.
| Grade | Availability | INCI | Key Benefits |
|---|---|---|---|
| Acrypol ET-1 | Liquid | Acrylate Copolymer |
|
| Acrypol ET-12 | Liquid | Acrylate Copolymer |
|
| Acrypol ET-22 | Liquid | Acrylates/Steareth-20 Methacrylate Copolymer |
|
| Acrypol ET-28 | Liquid | Acrylates/Beheneth-25 Methacrylate Copolymer |
|
| Acrypol ET-88 | Liquid | Acrylates/Steareth-20 Methacrylate Crosspolymer |
|
| Acrypol ET-S25 | Liquid | Acrylates/Beheneth-25 Methacrylate/HEMA Crosspolymer-2 |
|
These Acrypol grades are used to thickens and provide transparent appearance of formulation at low pH.
| Grade | Availability | INCI | Key Benefits |
|---|---|---|---|
| Acrypol AT-100 | Liquid | Oleyl Amine Ethoxylate |
|
| Acrypol ST-100 | Powder | Acrylic Polymer |
|
These are quick gel former and provide medium to high viscosity in formulation. They are also suitable for emulsion base formulations.
| Grade | Availability | INCI | Key Benefits |
|---|---|---|---|
| Acypol 640NT | Powder | Sodium Carbomer |
|
| Acrypol 641NT | Powder | Sodium Carbomer |
|
Pharmaceuticals
Acrypol polymers are highly efficient gel matrix formers for controlling drug release in solid dosage forms. The polymers have demonstrated slower drug release rates at lower concentrations than other commercially available excipients, enabling overall formulation cost savings and smaller tablet sizes.
| Grades | Pharmacopoeial Monographs | (%) solution | Viscosity# (cps) (at pH 7.3-7.8) |
|---|---|---|---|
| Acrypol 934P | USP/NF : Carbomer 934P | 0.5 | 29,400-39,400 |
| Acrypol 974P* | USP/NF : Carbomer Homopolymer Type B, EP : Carbomers | 0.5 | 25,000-45,000 |
| Acrypol 971P* | USP/NF : Carbomer Homopolymer Type A, EP : Carbomers | 0.5 | 4,000-11,000 |
| Acrypol 971G* | USP/NF : Carbomer Homopolymer Type A, EP : Carbomers | 0.5 | 4,000-8,000 |
| Acrypol 912G* | In house | - | - |
Acrypol polymers are used at very low concentrations (less than 1%) to produce a wide range of viscosities and flow properties in lotions, creams, gels, oral suspensions and in transdermal gel reservoirs.
| Grades | Pharmacopoeial Monographs | (%) solution | Viscosity# (cps) (at pH 7.3-7.8) |
|---|---|---|---|
| Acrypol 940 | USP/NF : Carbomer 940 | 0.5 | 40,000-60,000 |
| Acrypol 980* | USP/NF : Carbomer Homopolymer Type C, EP : Carbomers | 0.5 | 40,000-60,000 |
| Acrypol 934 | USP/NF : Carbomer 934 | 0.5 | 30,500-39,400 |
| Acrypol 934P | USP/NF : Carbomer 934P | 0.5 | 29,400-39,400 |
| Acrypol 974P* | USP/NF : Carbomer Homopolymer Type B, EP : Carbomers | 0.5 | 25,000-45,000 |
| Acrypol 941 | USP/NF : Carbomer 941 | 0.5 | 4,000-11,000 |
| Acrypol 971* | USP/NF : Carbomer Homopolymer Type A, EP : Carbomers | 0.5 | 4,000-11,000 |
Acrypol polymers can be used in oral care applications such as toothpastes and ulcer gels, desensitizing and whitening products. These polymers primarily function as efficient thickeners and co-binders at low usage level. The viscoelastic structure of Acrypol polymers imparts shear-thinning rheology and low thixotropy, which enables a clean ribbon of toothpaste to be extruded from the tube.
| Grades | Pharmacopoeial Monographs | (%) solution | Viscosity# (cps) (at pH 7.3-7.8) |
|---|---|---|---|
| Acrypol 980* | USP/NF : Carbomer Homopolymer Type C, EP : Carbomers | 0.5 | 40,000-60,000 |
| Acrypol 934P | USP/NF : Carbomer 934P | 0.5 | 29,400-39,400 |
| Acrypol 974P* | USP/NF : Carbomer Homopolymer Type B, EP : Carbomers | 0.5 | 25,000-45,000 |
| Acrypol 971P* | USP/NF : Carbomer Homopolymer Type A, EP : Carbomers | 0.5 | 4,000-11,000 |
| Acrypol 956 | In house | - | 20,000-41,000 |
These polymeric emulsifiers have high oil loading capacity and thickening property in oil-in-water topical formulations.
| Grades | Pharmacopoeial Monographs | (%) solution | Viscosity# (cps) (at pH 7.3-7.8) |
|---|---|---|---|
| Acrypol TR-1* | USP/NF : Carbomer Copolymer Type B, EP : Carbomers | 1.0 | 10,000-26,500 |
| Acrypol TR-2* | USP/NF : Carbomer Copolymer Type A, EP : Carbomers | 1.0 | 4,500-13,500 |
Suspension of insoluble ingredients in oral and topical liquids/semisolids.
| Grades | Pharmacopoeial Monographs | (%) solution | Viscosity# (cps) (at pH 7.3-7.8) |
|---|---|---|---|
| Acrypol ELT-31* | In house | 1.0 | 2,500-6,000 |
- Thickening efficiency High viscosity at low concentration
- Uniform performance Carbomer gives uniform viscosity performance, while natural gums vary in their performance
- Temperature Stability There is no significant effect of temperature on polymer
- Unaffected by aging Excellent shelf life
- Microbial Resistance Resists bacterial attack and does not support mould growth
- Versatility Although primarily used in aqueous systems with neutralization, it can also be used in solvent systems, with or without neutralization
- Elegance Smooth and luxurious feeling
Acrypol range is a high molecular weight polymer. It cannot be absorbed by body, thus it is totally safe for human consumption. Test for toxicological tolerance shows that it does not have any pronounced, physiological action and is non-toxic.
Dermal irritation (in vitro test) - non irritant
Eye irritation (in vitro test) - non irritant
Skin sensitization (max. test) - non sensitizing
Acrypol range is highly hygroscopic in supplied form, it contains maximum of 2.0% moisture. When exposed to open air at room temperature and 50% relative humidity, its equilibrium moisture uptake is 8.0%. All moisture uptake does not affect its efficiency but polymer with high level of moisture is more difficult to disperse and weigh accurately. So, Acrypol polymers must be stored in a tightly closed container and away from direct contact with water and excessive humid conditions.
Acrypol polymer's efficiency will not get affected up to two hours at temperatures below 104°C. When it is exposed to excessive temperatures, it can be plasticized and lose its characteristics.
- Powder form - Three years retest from date of manufacturing in intact condition
- Liquid form - One year from date of manufacturing in intact condition
Note: - Based on our testing, dry Acrypol polymers should last for years if stored properly and protected from moisture and extreme temperature
- Powder form - 20 kg net in corrugated box with polyethylene liner
- Liquid form - 60 kg plastic carboys and 200 kg plastic drum